PAPP-A ( Pregnancy Associated Plasma Protein-A)

PAPP-A is a pregnancy associated protein produced by the embryo and the placenta(syncytiotrophoblasts) and interact with insülin like growth factors playing a role in the growth of placenta and the fetus. It binds to the surface of the cells and releases bioactive IGF (Insulin Growth Factor. A correlation between PAPP-A levels in the first trimester of gestation and the development of metabolic complications during pregnancy has been reported.
Interpretation: PAPP-A is currently used in the first trimester pregnancy complications primarily among Down Syndrome pregnancy screening tests. A low PAPP-A value may be associated with a lower baby weight, increased chance of an early birth or a miscarriage in the second half of the pregnancy. With a high NT, a Down Syndrome pregnancy may be suspected.
Sample: Arm vein blood Nonfasting
Working day: Everyday
Result Time: 3 days 6:00 PM