Immunofixation Electrophoresis (IF)

Immunofixation allows the detection and typing of monoclonal (spesific) antibodies or immunglobulins in serum or urine. It is of great importance for the diagnosis and monitoring of certain blood disorders such as myeloma. Multiple myeloma also called as plasma cell myeloma, is a cancer of plasma cells, a type of a white blood cell that normally produces antibodies. In progress of the illness, bone pain, anemia, kidney dysfunction and infections may occur. Complications may also be amyloidosis (a group of abnormal proteins build up in tissue).
Interpretation:If the test result is positive for an unexpected protein band, the existence of a paraprotein (monoclonal protein, abnormal protein, M protein) band, with the reduction of other normal immunoglobulins is observed. One ype of this paraprotein is Bence Jones protein which is a urinary paraprotein (an abnormal immunoglobulin produced by the tumor clone). People without evidence of a paraprotein (3%)may have nonsecretory myeloma (not producing immunoglobulins).
Sample: Arm vein blood. Nonfasting
Working day: Tuesday,Thursday
Result Time: 4 days 6:00 PM