Creatinine Kinase (CK) is the enzyme that transfers phosphate groups from high-energy phosphate donor molecules (ATP-Adenosine Triphosphate) to special acceptor, that is, substrate molecules. Thus, it plays an important role in energy metabolism. The enzyme Creatine Kinase has three isoenzymes. These are CK-MM, CK-MB and CK-MM. CK-MM is specific for skeletal muscle. CK-MB is specific to myocardial muscle and CK-BB is specific to brain and lungs. If any of these tissues are damaged, these specific enzymes are secreted into the blood.
Interpretation:If CK is high and there is no diagnosis of kidney disease, there is an excess of one of the CK isoenzymes in the blood. CK-MB is of specific importance as it is a cardiac muscle related isoenzyme. CK-MB (CPK-2) increases 3-6 hours after a heart attack. Its levels peak at 12-24 hours and return to normal 12-48 hours after tissue death. It is also elevated in defibrillation (purposeful medical shock), electrical injuries, inflammation of the heart muscle (Myocarditis), and open heart surgery.
Sample: Venous blood from arm. It does not require hunger.
Working day: Every day
Result Time: same day in 2 hours
