Beta-2 Glycoprotein 1 IgM

Beta-2 Glycoprotein 1, is also known as Apolipoprotein H. One of its functions is binding cardiolipin, a kind of phospholipid whose function is the regulation of various mitochondrial proteins (energy factory of the cell), such as electron transport complexes, carrier proteins and phosphokinase enzymes and organization of mitochondrial structural proteins. Antibodies directed to Beta-2 Glycoprotein 1 (IgA, IgM, IgG) targets the phospholipids on the surface of the cells includind the platelets. This test therefore, is an indicator of blood clotting process .
Interpretation:In normal condutions, Beta-2 Microglobulin 1 Antibodies are not present in blood. If it is positive, Antiphospholipid Syndrome (APS) is the resultant disorder. This condution is associated with widespread blood clots (thrombotic episodes), a low platelet count (thrombocytopenia) or with pregnancy complications such as preeclampsia and reccurrent miscarriages especially in the first and second trimesters. There is also the possibility of autoimmune disorders like Systemic Lupus Erythromatosis (SLE).
Sample: Arm vein blood. Nonfasting
Working day: Saturday
Result Time: Monday 6:00 PM