When a blood vessel is injured, the body starts hemostasis to create clot. This fıunction needs coagulation factors. Antithrombin is a substance in the blood that regulates this process by limiting the blood’s ability to clot. It is the antibody against thrombin which is necessary to obtain clotting. Antithrombin also inhibits Factors Xa and IXa which are necessary to make thrombin. In this way, excessive clotting (thrombosis) is prevented.
Interpretation: If Antithrombin activity is lower than normal ranges, this may be due to inherited or acquired antithrombin deficiency. The patient has increased risk of developing blood clots especially in deep veins, the condution which is known as Deep Venous Thrombosis (DVP). Extensive thrombosis leads to Disseminated Intravascular Coagulation (DIC), blood loss, cancer, nephrotic syndrome, liver diseases, pulmonary embolism.
Sample: Arm vein plasma(Citrate). Nonfasting
Working day: Thursday
Result Time: Next day 6:00 PM
