Varicella Zoster Virus is a DNA virus that is a member of the Herpesvirus group. VZV locates itself in the sensory nerve ganglia , after the primary infection. It is a rash associated (chickenpox) virus which is highly contagious especially in childhood. It is characterized by rashes after 10-21 days, following exposure forming shingles. These are mostly painful lesions. It there is primary infection in adulthood, especially in pregnant women, the virus passes through placenta to the fetus causing congenital disease of the infant.
Interpretation:IgG ang IgM are the antibodies against the VZV virus but Ig M appears in the early infection and IgG appears after 10-14 days. If IgG is positive with IgM negative, this indicates a past infection or vaccinatination. If IgG is and IgM are both positive this indicates this indicates a recent infection with VZV virus. If they are both negative this indicates the absence of exposure but the sample may be drawn before the appearance of detectable antibodies (very early infection). The test should be repeated in 2-3 weeks to eliminate the doubted exposure risk.
Sample: Arm vein blood.Various body fluids Nonfasting
Working day: Tuesday
Result Time: Friday 6:00 PM