Creatinine is a molecule which is the end product of the energy consumption of the muscles. After the metabolisation process of the energy molecule (ATP-Adenosine Triphosphate) creatinine is released in blood , with a constant rate of daily routine energy consumption, where the levels are stable. Almost all creatinine is cleared from the blood by kidneys. It is mostly used to measure the ability of kidneys of clearing creatinine from the blood. Therefore, it is considered as a glomerular filtration rate measurement. Creatinine exists in the urine. A measurement of creatinine in the blood and urine (24 hours collected urine) , gives the glomerular filtration rate (GFR) according to the ml/min and body surface area included equation. This is called the Creatinine Clearance Test. However, shorter time periods for urine samples may be used, considering the accurate timing and collection procedure of the sample which the doctor defines.
Interpretation:This test is a measure of how well the kidneys filter creatinine out of the blood stream ınto the urine. Results should be interpreted by the doctor according to sampling, age and gender. If creatinine alone is increased in blood, impaired renal function may be suspected and further tests should be investigated. Recently, elevated creatinine levels in infants have been found associated with bacteremia and increased prostate cancer risk for men.
Sample: Arm vein blood, 24 hour or spot urine. Nonfasting
Working day: Everyday
Result Time: Same day 6:00 PM