Creatine Isoenzymes (CK-Isoenzymes)

Creatinine Kinase (CK) is the enzyme that transfers phosphate groups from high-energy phosphate donor molecules (ATP-Adenosine Triphosphate) to special acceptor, that is, substrate molecules. Thus, it plays an important role in energy metabolism. The enzyme Creatine Kinase has three isoenzymes. These are CK-MM, CK-MB and CK-MM. CK-MM is specific to skeletal muscle. CK-MB is specific to myocardial muscle and CK-BB is specific to brain and lungs. If any of these tissues are damaged, these specific enzymes are secreted into the blood.
Interpretation:If CK is found high in the blood, it is not caused by kidney disease but by overproduction of the enzyme. Therefore, it is necessary to identify the tissue in which it is overproduced. Because CK-BB (CPK1) is found in the brain and lungs, this may be due to brain cancer, brain injury, electroconvulsive therapy, pulmonary infarction, or seizures. CK-MB (CPK-2) increases 3-6 hours after a heart attack. Its levels peak at 12-24 hours and return to normal 12-48 hours after tissue death. It is also elevated in defibrillation (purposeful medical shock), electrical injuries, inflammation of the heart muscle (Myocarditis), and open heart surgery. CK-MM (CPK-3) height can be caused by muscle damage or muscle stress. These include impact injuries, muscle damage caused by drugs, muscular dystrophy, myocyte (skeletal muscle inflammation), multiple intramuscular injections, physiological tests for nerve and muscle functions (electromyelography-EMG), recent seizures, and stenosis exercise (passing through the spine). recommended exercises due to the narrowing of the nerve channels).
Sample: Venous blood from arm. It does not require hunger.
Working day: Consult the lab
Result Time: Consult the lab