SS-A and SS-B antibodies are nuclear antibodies (anti-nuclear antibodies) that can be observed in patients with rheumatic diseases. SS-A antibodies are found in 50% of patients with Sjorgen syndrome (in which the immune system mistakely attacks the body’s cells and tissues). The reason for the development of this syndrome is unknown. It may occur due to specific genes or a triggering mechanism such as infections. Although the disease can occur at any age, it is mainly seen over 40.
Interpretation:In Sjogren’s Syndrome, the immune system first attacks the glands that produce tears and saliva. However, it can also attack the thyroid, joints, liver, nerves, kidneys, lungs, and skin. Dental cavities, lungs and kidneys, visual functions, lymph nodes and nerves may be affected due to complications. While SS-A antibodies are specific to Sjorgen Syndrome (50%), they can also be found in some healthy people and patients with immune diseases. Therefore, it alone does not provide a definitive diagnosis for Sjorgen Syndrome. However, there is no reference value, and the result should be negative under ordinary conditions.
Sample: Venous blood taken from the arm. Nonfasting.
Working day: Tuesday, Friday
Result Time: 4 days at 6 pm
